APOBEC3G: A human protein that interferes with the replication of HIV by incorporating itself into virus particles and damaging the genetic material of the virus. The viral protein Vif can halt this process in two ways: (1) by binding to APOBEC3G and preventing it from incorporating into virus particles; and (2) by targeting APOBEC3G for destruction and almost completely eliminating it from the cell. APOBEC3G stands for apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G.
- Apolipoprotein A-I
Apolipoprotein A-I: APOA-I. The major protein component of HDL (high density lipoprotein) and a relatively abundant plasma protein. APOA-I is instrumental in promoting the transfer of cholesterol into the liver where it is metabolized and then excreted via the intestine from the body. The gene locus for APOA-I is on chromosome 11q23. A number of […]
- Apolipoprotein E
Apolipoprotein E: A type of lipoprotein (a protein connected to a fat). Apolipoprotein E is abbreviated ApoE and the gene that encodes it is known as APOE. APOE is located on chromosome 19 in band 19q13.2. Lipoproteins are responsible for carrying cholesterol and other fats through the bloodstream as little packages and are essential for […]
Apollo: In Greek mythology, often considered to be a god of healing. In stories such as The Iliad, Apollo is depicted as the bringer and reliever of plagues.
Apophenia: In psychology, the perception of connections and meaningfulness in unrelated things. Apophenia can be a normal phenomenon or an abnormal one, as in paranoid schizophrenia when the patient sees ominous patterns where there are none.
- Apophysitis calcaneus
Apophysitis calcaneus: Also called Sever’s condition, this disorder is due to inflammation of the growth plate of the calcaneus, the bone at the back of the heel. The inflammation is at the point where the Achilles tendon attaches. It occurs mainly in older children and adolescents, especially active boys. It can be very painful. It […]