Asplenic: Pertaining to asplenia, the state of being without a spleen or without a functional spleen. The spleen can be functionally destroyed, as by inadequate oxygen supply in sickle cell disease.
The spleen, an organ located in the upper left part of the abdomen near the stomach, produces lymphocytes, filters blood, serves as a major reservoir for blood and destroys blood cells that are aged. It also has an important function in the filtering, phagocytosis (ingestion and digestion) and removal of bacteria from the bloodstream. Asplenic patients run a significantly increased risk of severe sepsis (bloodstream infection).
The prefix “a-” comes from the Greek meaning “not.”
Assay: An assay is an analysis done to determine: The presence of a substance and the amount of that substance. Thus, an assay may be done for example to determine the level of thyroid hormones in the blood of a person suspected of being hypothyroid (or hyperthyroid). The biological or pharmacological potency of a drug. […]
- Assay, CEA
Assay, CEA: CEA (carcinoembryonic antigen) is a protein found in many types of cells but associated with tumors and the developing fetus. CEA is tested in blood. The normal range is
- Assay, NSE
Assay, NSE: Neuron-specific enolase (NSE) is a substance that has been detected in patients with certain tumors, namely: neuroblastoma, small cell lung cancer, medullary thyroid cancer, carcinoid tumors, endocrine tumors of the pancreas, and melanoma. Studies of NSE as a tumor marker have concentrated primarily on patients with neuroblastoma and small cell lung cancer. Measurement […]
- Assembly and budding
Assembly and budding: A portion of the processes by which new HIV is formed in infected host cells. Viral core proteins, enzymes, and RNA gather (assemble) just inside the cell’s membrane, while the viral envelope proteins aggregate within the membrane. An immature viral particle is formed and then pinches off (buds) from the cell, acquiring […]
- Assembly, DNA
Assembly, DNA: The process of putting fragments of DNA that have been sequenced into their correct chromosomal positions. The pieces of DNA are assembled to reconstitute the sequence of the chromosome from which they came.