Blot, Northern: A technique in molecular biology, used mainly to separate and identify pieces of RNA.
Called a Northern blot only because it is similar to a Southern blot (which is named after its inventor, the British biologist M.E. Southern). There is also a Western blot.
- Blot, Southern
Blot, Southern: A test commonly used in molecular biology and genetics, the purpose of the test being to check for a match between DNA molecules. In the Southern blot technique, DNA fragments are separated by a method called agarose gel electrophoresis, transferred (blotted) onto membrane filters, and hybridized with complementary radiolabeled probes. The aim is […]
- Blot, Western
Blot, Western: A technique in molecular biology that is used to separate and identify proteins. It is called a Western blot merely because it is similar to a Southern blot, which was named after its inventor, the British biologist M.E. Southern. For example, the Western blot assay method is commonly used to diagnose Lyme disease.
- Blue baby
Blue baby: A baby who is cyanotic (blue), due usually to a heart malformation that prevents the baby’s blood from being fully oxygenated. The bluish color reflects the deoxygenated state of the blood. (Oxygenated blood is red.) Sometimes the term “blue baby” is also applied to a child who is cyanotic due to failure by […]
- Blue baby operation
Blue baby operation: A surgical procedure for a baby who is cyanotic (blue) due to a heart malformation that prevents blood from being fully oxygenated. The bluish color reflects the deoxygenated state of the blood. The surgery is designed to palliate or ideally correct the heart defect and relieve the cyanosis. The term originated with […]
- Blue cohosh
Blue cohosh: (Caulophyllum thalictroides). A tall North American perennial plant with large blue berries. Blue cohosh is sold as an herbal dietary supplement that can induce labor. Blue cohosh contains the glycosides caulosaponin and caulophyllosaponin, which cause uterine contraction and constriction of the coronary arteries in experimental animals. There is considerable concern about the medical […]