Bone marrow biopsy: The removal of a sample of bone marrow and a small amount of bone through a large needle. Two samples are taken. The first is bone marrow by aspiration (suction with a syringe). The second is a core biopsy to obtain bone marrow along with bone fibers. After the needle is removed, this solid sample is pushed out of the needle with a wire. Both samples are examined under a microscope to examine the cells and the architecture of the bone marrow.
- Bone marrow transplant
Bone marrow transplant: A procedure in which bone marrow that is diseased or damaged is replaced with healthy bone marrow. The bone marrow to be replaced may be deliberately destroyed by high doses of chemotherapy and/or radiation therapy. The replacement marrow may be the patient’s own marrow or it may come from another person. If […]
- Bone mass density (BMD)
Bone mass density (BMD): A measure of bone density. Loss of bone mass is due to osteopenia or, if more severe, to osteoporosis.
- Bone mineral density
Bone mineral density: BMD, a measure of bone density, reflecting the strength of bones as represented by calcium content. The BMD test detects osteopenia (mild bone loss, usually without symptoms) and osteoporosis (more severe bone loss, which may cause symptoms). See also: Bone mass density, Osteopenia, Osteoporosis.
- Bone morphogenetic protein
Bone morphogenetic protein: A member of a superfamily of proteins that promote the formation of bone and the skeleton and help mend broken bones. Although it was known that scrapings from healthy bone stimulated the healing of fractures, the nature of the regenerative mechanism remained a mystery until 1965 when Dr. Marshall Urist did an […]
- Bone morphogenic protein 2
Bone morphogenetic protein 2: A protein that induces the formation of bone and cartilage. Bone morphogenic protein 2 (which is symbolized BMP2) belongs to a superfamily called transforming growth factor beta (TGF-beta). The gene for BMP2 is on chromosome 20 in band 20p12.3. Three sets of variations within the BMP2 gene reportedly triple the risk […]