Breast cancer gene

Breast cancer gene: One of the genes that contributes to breast cancer. See also: BRCA breast cancer gene.

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  • Breast cancer gene BRCA1

    Breast cancer gene BRCA1: A gene that normally acts to restrain the growth of cells in the breast but, when mutated, predisposes to breast cancer. BRCA1 and BRCA2 were the first breast cancer genes to be identified. Mutated forms of these genes are believed to be responsible for about half the cases of inherited breast […]

  • Breast cancer metastasis suppressor 1 (BRMS1)

    Breast cancer metastasis suppressor 1 (BRMS1): A gene that plays a role in preventing the metastasis (spread) of breast cancer to other parts of the body and so may improve breast cancer survival. The BRMS1 gene is on chromosome 11.

  • Breast cancer susceptibility genes

    Breast cancer susceptibility genes: Inherited factors that predispose to breast cancer. Put otherwise, these genes make one more susceptible to the disease and so increase the risk of developing breast cancer. Two of these genes, BRCA1 and BRCA2, have been identified (and prominently publicized). Several other genes (those for the Li-Fraumeni syndrome, Cowden disease, Muir-Torre […]

  • Breast cancer, familial

    Breast cancer susceptibility genes; familial breast cancer, BRCA1; BRCA2.

  • Breast cancer, male

    Breast cancer, male: Breast cancer in men. Male breast cancer is much less common than breast cancer in women. Fewer than 1 percent of persons with breast cancer are male. However, breast cancer is no less dangerous in males than in females. After the diagnosis of breast cancer is made, the mortality rates are virtually […]

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