Carcinoid tumor: A tumor which secretes large amounts of the hormone serotonin. Carcinoid tumor is also called an argentaffinoma. The tumor usually arises in the gastrointestinal tract, anywhere between the stomach and the rectum (the favorite spot is in the appendix) and from there may metastasize (spread) to the liver. In the liver the tumor produces and releases large quantities of serotonin into the systemic bloodstream.
The consequences are called the carcinoid syndrome . It is directly due to the serotonin and includes flushing and blushing, swelling of the face (especially around the eyes), flat angiomas (little collections of dilated blood vessels) on the skin, diarrhea, bronchial spasm, rapid pulse, low blood pressure and tricuspid and pulmonary stenosis (narrowing of the tricuspid and pulmonic valves of the heart), often with regurgitation.
One or more of four kinds of treatment are used for carcinoid tumors: surgery (to take out the cancer); radiation therapy (using high-dose x-rays to kill the cancer cells); biological therapy (using the body’s natural immune system to fight the cancer); and chemotherapy (using drugs to kill cancer cells).
Carcinoid tumors are considered a type of endocrine tumor since they secrete a hormone (serotonin). They can occur as part of certain genetic disorders such as the multiple endocrine neoplasia (MEN) type 1 and neurofibromatosis type 1 (NF1 or von Recklinghausen disease).
Cancer that begins in the skin or in tissues that line or cover body organs. Examples are carcinoma of the breast, colon, liver, lung, pancreas, prostate, or stomach.
- Carcinoma in situ
Carcinoma in situ: Cancer that has stayed in the place where it began and has not spread to neighboring tissues (for example, squamous cell carcinoma in situ).
- Carcinoma in situ, squamous cell
Carcinoma in situ, squamous cell: An early stage of skin cancer that develops from squamous cells (the flat, scale-like cells in the outer layer of the skin). The hallmark is a persistent, progressive, slightly raised, red, scaly, or crusted plaque that may occur anywhere on the skin surface or on mucosal surfaces, such as in […]
- Carcinoma of the breast, infiltrating ductal
Carcinoma of the breast, infiltrating ductal: One of several recognized specific patterns of cancer of the breast, so named because it begins in the cells that form the ducts of the breast. It is the most common form of breast cancer. On a mammogram, invasive ductal carcinoma is usually visualized as a mass with fine […]
- Carcinoma of the breast, infiltrating lobular
Carcinoma of the breast, infiltrating lobular: The second most common type of invasive breast cancer. Infiltrating lobular carcinoma starts in the glands that secrete milk (lobules). On a mammogram, a lobular carcinoma can look similar to a ductal carcinoma, appearing as a mass with fine spikes radiating from the edges (spiculation). Infiltrating lobular carcinoma can […]