Chancroid: A sexually transmitted infection (STI) caused by the bacterium Haemophilus ducreyi. Periodic outbreaks of chancroid have occurred in the US, usually in minority populations in the inner cities. This disease is common in sub-Saharan Africa among men who have frequent contact with prostitutes.
The infection begins with the appearance of painful open sores on the genitals, sometimes accompanied by swollen, tender lymph nodes in the groin. These symptoms occur within a week after exposure. Symptoms in women are often less noticeable and may be limited to painful urination or defecation, painful intercourse, rectal bleeding, or vaginal discharge.
Chancroid can be treated effectively with several antibiotics. Chancroid is one of the genital ulcer diseases associated with an increased risk of transmission of the human immunodeficiency virus (HIV), the cause of AIDS.
Also known as soft chancre, soft sore, and soft ulcer.
- Chandipura virus
Chandipura virus: A virus that causes fever, symptoms similar to those of flu, and acute encephalitis (inflammation of the brain). Chandipura virus was first isolated in 1965 in a village in Maharashtra State, India. Since then, the virus has been reported in adjoining states in central India. The likely vector (carrier) of the virus is […]
- Change, single base
Change, single base: A change in which a single base in the DNA differs from the usual base at that position. These single base changes are also called SNPs or “snips.” Millions of SNP’s have been cataloged in the human genome. Some SNPs such that which causes sickle cell are responsible for disease. Other SNPs […]
Channelopathy: A disease involving dysfunction of an ion channel. Channelopathies are known that involve the ion channels for potassium, sodium, chloride and calcium. There are also channelopathies involving the acetylcholine receptor, the glycine receptor, and other receptors. Each channelopathy can play a role in a number of different diseases. For example, the calcium channelopathies include […]
Chaperone: 1. Any protein that is required for the proper folding or assembly of another protein or protein complex without being a component of the final structure. 2. A woman who is present when a male physician examines a female patient. 3. Anyone present when a physician examines a patient of the opposite sex from […]
- Chapped lips
Chapped lips: Dry, cracked or sore lips, usually in cold, windy, dry weather and less often in warm weather. Sun exposure can contribute to chapping of the lips. Licking or biting the lips is often a contributing factor. The lips are more sensitive to chapping than the skin. Unlike the skin, the lips do not […]