The most common type of steroid in the body. Cholesterol has a reputation for being associated with an increased risk for heart and blood vessel disease. However, cholesterol is essential to the formation of bile acids, vitamin D, progesterone, estrogens (estradiol, estrone, estriol), androgens (androsterone, testosterone), mineralocorticoid hormones (aldosterone, corticosterone), and glucocorticoid hormones (cortisol). Cholesterol is also necessary to the normal permeability and function of the membranes that surround cells. A diet high in saturated fats tends to increase blood cholesterol levels, whereas a diet high in unsaturated fats tends to lower blood cholesterol levels. Although some cholesterol is obtained from the diet, most cholesterol is made in the liver and other tissues. The treatment of elevated cholesterol involves not only diet but also weight loss, regular exercise, and medications. After the age of 20, cholesterol testing is recommended every 5 years.
- Cholesterol ester transfer protein
Cholesterol ester transfer protein: A protein that helps regulate the size of cholesterol particles and influence the process of atherogenesis (the formation of plaques in arteries). Abbreviated CETP. The CETP gene is in chromosome band 16q21. A number of mutations are known in the CETP gene. Some result in CEPT deficiency, increased levels of HDL […]
- Cholesterol guidelines
those with moderate risk (2 or more risk factors plus an under 10 percent risk of a heart attack in 10 years) or those with 0 to 1 risk factor. According to the report, the absolute benefits for people at the lower levels of risk are less clear cut and the recent clinical trials do […]
- Cholesterol lowering with fibrate
Cholesterol lowering with fibrate: The fibrates are cholesterol-lowering drugs that are primarily effective in lowering triglycerides and, to a lesser extent, in increasing HDL-cholesterol levels. Gemfibrozil (brand name: LOPID), the fibrate most widely used in the United States, can be very effective for patients with high triglyceride levels. However, it is not very effective for […]
- Cholesterol lowering with niacin
Cholesterol lowering with niacin: Niacin or nicotinic acid, one of the water-soluble B vitamins, improves all lipoproteins when given in doses well above the vitamin requirement. Nicotinic acid lowers the total cholesterol, “bad” LDL-cholesterol, and triglyceride levels, while raising the “good” HDL-cholesterol level. There are two types of nicotinic acid: immediate release and timed release. […]
- Cholesterol, "good"
High-density lipoprotein (HDL) cholesterol.