Colitis, pseudomembranous: Severe inflammation of the inner lining of the colon due usually to the Clostridium difficult (C. difficile) bacterium, one of the most common causes of infection of the large bowel (colon) in the United States, affecting millions of patients yearly. Patients taking antibiotics are at risk of becoming infected with C. difficile. Antibiotics disrupt the natural bacteria of the bowel, allowing C. difficile bacteria to become established in the colon. Many persons infected with C. difficile bacteria have no symptoms. These people become carriers of the bacteria and can infect others. In some people, a toxin produced by C. difficile causes diarrhea, abdominal pain, severe inflammation of the colon (colitis), fever, an elevated white blood count, vomiting and dehydration. Rarely, the colon becomes dilated (megacolon) or the walls of the colon wear away and holes develop (colon perforation), which can lead to a life-threatening infection of the abdomen.
- Colitis, spastic
Colitis, spastic: A common gastrointestinal disorder involving an abnormal condition of gut contractions (motility) characterized by abdominal pain, bloating, mucous in stools, and irregular bowel habits with alternating diarrhea and constipation, symptoms that tend to be chronic and to wax and wane over the years. Although the spastic colitis can cause chronic recurrent discomfort, it […]
- Colitis, ulcerative
Colitis, ulcerative: A bowel disease that is characterized by inflammation with ulcer formation in the lining of colon (large intestine). Its cause is unknown. The end of the colon (the rectum) is generally involved. When limited to the rectum, the disease is called ulcerative proctitis. The inflammation may extend to varying degrees into the upper […]
- Colitis, universal
Colitis, universal: Ulcerative colitis that involves the entire colon (large intestine).
Collagen: The principal protein of the skin, tendons, cartilage, bone, and connective tissue. Collagen is an essential part of the framework of the design of our various body tissues.
- Collagen disease
Collagen disease: A disease that damages collagen or other components of connective tissue. For example, dermatomyositis and systemic lupus erythematosus are collagen diseases.