Coloboma: A congenital malformation (birth defect) in which part of the eye does not form due to failure of fusion of an embryonic feature called the intraocular fissure. The resultant coloboma can be likened to a missing slice from a pie that may involve a number of different structures within the eye including the choroid, iris, lens, optic nerve, and retina.
A coloboma can occur as an isolated defect in an otherwise normal baby, or it can be part of a multiple congenital malformation syndrome such as the cat-eye syndrome (named after the coloboma which gives the eye something of a feline look). Colobomas are also seen in the aniridia-Wilms tumor association (the concurrence of undergrowth of the iris of the eye and Wilms tumor of the kidney); and the trisomy 13 syndrome (a disastrous disease due to an extra chromosome number 13).
Colon: The long, coiled, tubelike organ that removes water from digested food. The remaining material, solid waste called stool, moves through the colon to the rectum and leaves the body through the anus. Also known as large bowel and large intestine.
- Colon cancer
A malignant tumor arising from the inner wall of the large intestine (the colon). In the US, colon cancer is the third leading type of cancer in males and the fourth in females. Risk factors for cancer of the colon and rectum (colorectal cancer) include colon polyps, long-standing ulcerative colitis, and genetic family history. Most […]
- Colon cancer family history
Colon cancer family history: A family history of colorectal cancer (CRC). First-degree relatives of people with CRC are themselves at a 2 to 3-fold increased risk of colorectal cancer. (Parents, brothers and sisters, and children are first-degree relatives.) When the family history includes 2 or more relatives with CRC, the possibility of an inherited CRC […]
- Colon cancer and polyps
Benign tumors of the large intestine are called polyps. Malignant tumors of the large intestine are called cancers. Benign polyps do not invade nearby tissue or spread to other parts of the body. Benign polyps can be easily removed during colonoscopy, and are not life threatening. If benign polyps are not removed from the large […]
- Colon polyp
A benign tumor of the large intestine. Benign polyps do not invade nearby tissue or spread to other parts of the body. Benign polyps can easily be removed during colonoscopy and are not life threatening. If benign polyps are not removed from the large intestine, they can become malignant (cancerous) over time. Most cancers of […]