Connexin 26


Connexin 26: Also known as gap junction beta 2, or GJB2. See: GJB2. See also: Connexin.

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    Connexon: A special type of protein composed of an assembly of six subunits that are called connexins. A connexon of one cell is joined to that of an adjacent cell to form an intercellular channel consisting of 12 connexin subunits. Clusters of intercellular channels are known as a gap junction because of the minute extracellular […]

  • Conor and Bruch disease

    Conor and Bruch disease: African tick typhus, one of the tick-borne rickettsial diseases of the eastern hemisphere similar to Rocky Mountain spotted fever but less severe. Characteristic features include fever, a small ulcer (tache noire) at the site of the tick bite, swollen glands nearby (satellite lymphadenopathy), and a red raised (maculopapular) rash. Also called […]

  • Conotoxin

    Conotoxin: A toxin made by cone snails (Conidae), also called cone shells, which are fish-eating snails that inhabit tropical coral reefs, mangroves and associated habitats. Each of the 500 species of cone snail produces roughly 50 to 100 distinct conotoxins which they use to immobilize prey. These toxins are selective in their receptor binding sites. […]

  • Consanguinity

    Consanguinity: Close blood relationship, sometimes used to denote human inbreeding. Mating of closely related persons can cause significant genetic disease in offspring. Everyone carries rare recessive genes that, in the company of other genes of the same type, are capable of causing autosomal recessive diseases. First cousins share a set of grandparents, so for any […]

  • Conservative mutation

    Conservative mutation: A change in a DNA or RNA sequence that leads to the replacement of one amino acid with a biochemically similar one. It is conservative in the sense that it is not a radical change that might, for example, stop all protein production.


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