Designer estrogen: An engineered drug that possesses some, but not all, of the actions of estrogen. Also known as selective estrogen-receptor modulator (SERM). For example, raloxifene (brand name: Evista) is classified as a designer estrogen because, like estrogen, it prevents bone loss and lowers serum cholesterol; however, it does not stimulate the endometrial lining of the uterus.
- Designer steroid
Designer steroid: A synthetic steroid derived by simple chemical modification from another steroid, usually an anabolic steroid. Anabolic steroids, which build muscle mass, can have serious long-term health consequences in men, women, and children.
- Desmoid tumor
Desmoid tumor: A benign soft-tissue tumor that does not spread to other parts of the body. Desmoid tumors occur most often in young adults, and they usually involve the limbs or trunk, but they can also arise in the abdomen or thorax. Desmoid tumors are very difficult to remove because they adhere tenaciously to surrounding […]
Desmoplasia: The growth of fibrous or connective tissue anywhere in the body.
Desmoplastic: This term refers to the growth of fibrous or connective tissue. Some tumors elicit a desmoplastic reaction, the pervasive growth of dense fibrous tissue around the tumor. Scar tissue (adhesion) within the abdomen after abdominal surgery is another type of desmoplastic reaction. “Desmo-” comes from the Greek “desmos” meaning “a fetter or band” and […]
- Desmoplastic reaction
Desmoplastic reaction: A reaction that is associated with some tumors and is characterized by the pervasive growth of dense fibrous tissue around the tumor. The formation of scar tissue (adhesion) within the abdomen after abdominal surgery is another type of desmoplastic reaction.