Differential diagnosis: The process of weighing the probability of one disease versus that of other diseases possibly accounting for a patient’s illness. The differential diagnosis of rhinitis (a runny nose) includes allergic rhinitis (hayfever), the abuse of nasal decongestants and, of course, the common cold.
- Differential white cell count
Differential white cell count: The proportions of the different types of white cells in the blood, usually split into the different types of granulocytes, lymphocytes, monocytes, eosinophils, and basophils. The differential white cell count was originally done by visual inspection of the blood and is now often machine-generated. Normal values are: 24-62% neutrophils, 19-53% lymphocytes, […]
- Differentiated cancer
Differentiated cancer: A cancer in which the cells are mature and look like cells in the tissue from it arose. Differentiated cancers tend to be decidedly less aggressive than undifferentiated cancers composed of immature cells.
Differentiation: 1 The process by which cells become progressively more specialized; a normal process through which cells mature. This process of specialization for the cell comes at the expense of its breadth of potential. Stem cells can, for example, differentiate into secretory cells in the intestine. 2 In cancer, differentiation refers to how mature (developed) […]
- Differentiation therapy
Differentiation therapy: An approach to the treatment of advanced or aggressive malignancies in which the malignant cells are treated so that they can resume the process of maturation and differentiation into mature cells. Differentiation therapy is based on the concept that cancer cells are normal cells that have been arrested at or have gone back […]
- Diffuse degeneration of gray matter with cirrhosis
Diffuse degeneration of gray matter with cirrhosis: A progressive disease of the nervous system characterized by spasticity (tightness), myoclonus and dementia and by liver problems with jaundice and cirrhosis. This disorder, first described by Alpers in 1931 as “Diffuse progressive degeneration of gray matter of cerebrum”, usually begins early in life with convulsions. A continuous […]