Ehlers-Danlos syndrome, dermatosparaxis type: A genetic disorder characterized by extremely fragile and sagging skin caused by mutation in the ADAMTS2 gene. People with this form of Ehlers-Danlos syndrome have soft, doughy skin that is very fragile and bruises easily. The skin sags and wrinkles, and extra (redundant) folds of skin may be present as children get older. Joints are very loose, which can delay the development of motor skills such as sitting, standing, and walking. Infants with the condition are born with a soft out-pouching called a hernia around the belly-button. Other symptoms include a small chin, a blue tinge to the part of the eyeball that is usually white (the sclera), and mild overgrowth of body hair.
The ADAMTS2 gene makes an enzyme that helps process procollagen, a protein used to assemble collagen that provide structure and strength to connective tissue throughout the body. Mutations in the ADAMTS2 gene completely inactivate the enzyme made by the gene. As a result, procollagen is not processed, and collagen molecules cannot be assembled properly. These defects weaken connective tissue, particularly in the skin, causing the signs and symptoms of the condition.
This type of Ehlers-Danlos syndrome is inherited in an autosomal recessive manner. It was formerly called Ehlers-Danlos syndrome type VIIC.
Ehrlichiosis: An acute (abrupt onset) disease, first reported in humans in 1986, due to infection by the rickettsial agent, Ehrlichia canis. The brown dog tick, is the common vector (carrier). Ehrlichiosis is clinically similar to Rocky Mountain spotted fever with high fever, headache, malaise, and muscle pain but without a rash. Laboratory features include leukopenia […]
Having to do with the liver.
- Eicosapentaenoic acid
Eicosapentaenoic acid: One of the principal omega-3 fatty acids. Abbreviated EPA. The body has a limited ability to manufacture EPA by converting the essential fatty acid, alpha-linolenic acid (ALA) which is found in flaxseed oil, canola oil or walnuts.
Eicosanoid: A lipid mediator of inflammation derived from the 20-carbon atom arachidonic acid (20 in Greek is “eicosa”) or a similar fatty acid. The eicosanoids include the prostaglandins, prostacyclin, thromboxane, and leukotrienes.
Eidetic: 1. Marked by extraordinarily accurate and vivid recall, especially of images. 2. By extension, an individual with such exceptional powers. Eidetic memory is the ability to see in one’s mind’s eye in the most minute detail. From the German eidetisch, from the Greek eidetikos and eidos (form), and ultimately from the Indo-European root weid- […]