Evolution, biologic
Evolution, biologic: Biologic evolution was contrasted with cultural (social) evolution in 1968 by A.G. Motulsky who pointed out that biologic evolution is mediated by genes, shows a slow rate of change, employs random variation (mutations) and selection as agents of change, new variants are often harmful, these new variants are transmitted from parents to offspring, the mode of transmission is simple, complexity is achieved by the rare formation of new genes by chromosome duplication, biologic evolution occurs with all forms of life, and the biology of humans requires cultural evolution.
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- Evolutionarily conserved gene
Evolutionarily conserved gene: A gene that has remained essentially unchanged throughout evolution. Conservation of a gene indicates that it is unique and essential: There is not an extra copy of that gene with which evolution can tinker, and changes in the gene are likely to be lethal.
- Evolutionarily conserved sequence
Evolutionarily conserved sequence: A base sequence in a DNA molecule (or an amino acid sequence in a protein) that has remained essentially unchanged throughout evolution.
- Ewing sarcoma
Ewing sarcoma: A malignant tumor that arises in a primitive nerve cell within bone or soft tissue and affects children and adolescents, especially between ages 10 and 20. Ewing sarcoma usually appears in the large bones of the arms and legs and the flat bones of the pelvis, spine, and ribs. Treatments include chemotherapy, surgery, […]
- Exacerbate
Exacerbate: To make worse. For example, smoking may exacerbate lung disease.
- Exacerbation
Exacerbation: A worsening. In medicine, exacerbation may refer to an increase in the severity of a disease or its signs and symptoms. For example, an exacerbation of asthma might occur as a serious effect of air pollution, leading to shortness of breath.