Factor V
Factor V: A coagulation factor needed for the normal clotting of blood. Also known as proaccelerin.
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- Factor V Leiden
Factor V Leiden: A genetic disorder of blood coagulation (clotting) that carries an increased risk of venous thromboembolism — the formation of clots in veins that may break loose and travel through the bloodstream to the lungs or brain. On the molecular level, factor V Leiden is characterized by a G to A substitution at […]
- Factor VIII
Factor VIII: Factor eight, a key factor in the process of blood coagulation (clotting). Lack of normal factor VIII causes hemophilia (hemophilia A). The gene for classic hemophilia was long known to be on the X chromosome. Females carry the gene and transmit it to their hemophiliac sons. Female carriers are normal since they have […]
- Factor X
Factor X: A coagulation factor, a substance in blood essential to the normal clotting process. Production of factor X takes place in the liver and requires vitamin K. The gene for factor X is located on chromosome 13 and is in band 13q34. The “X” in factor X is the Roman numeral “ten.” (All numbered […]
- Factor, colony-stimulating
Factor, colony-stimulating: A laboratory-made agent similar to a normally existing substance in the body that stimulates the production of blood cells. The colony-stimulating factors (CSFs) include granulocyte colony-stimulating factors (G-CSF) and granulocyte-macrophage colony-stimulating factors (GM-CSF). Treatment with colony-stimulating factors can help the blood-forming tissue recover from the effects of chemotherapy and radiation therapy.
- Factor, rheumatoid
Factor, rheumatoid: An antibody that is measurable in the blood. Rheumatoid factor is commonly used as a blood test for the diagnosis of rheumatoid arthritis. Rheumatoid factor is present in about 80 percent of adults (and a much lower proportion of children) with rheumatoid arthritis. It is also present in patients with other connective tissue […]