Gage, Phineas


Gage, Phineas: The most famous patient to have survived severe damage to the brain and the first from whom something was learned about the relation between personality and the function of the front parts (the frontal lobes) of the brain.

During work on a railroad in 1848, an unplanned explosion propelled a rod through Gage’s head. Against all expectation, Gage survived. Once capable and responsible, Gage became profane, fitful, and obstinate – a man who was “no longer Gage.”

Read Also:

  • Gain-of-function mutation

    Gain-of-function mutation: A mutation that confers new or enhanced activity on a protein. Loss-of-function mutations, which are more common, result in reduced or abolished protein function.

  • Gait

    Gait: A manner of walking. Observation of gait can provide early diagnostic clues for a number of disorders, including cerebral palsy, Parkinson’s disease, and Rett syndrome.

  • Galactorrhea

    Galactorrhea: The spontaneous flow of milk from the nipple at any time other than during nursing. Galactorrhea can be due to “normal” factors such as an unrecognized pregnancy, trauma, surgery, overexercise or one of a number of drugs (including amphetamine, cimetidine, female hormone replacement therapy, hydroxyzine, methyldopa, nicotine, narcotics, reserpine, antidepressants of the so-called tricyclic […]

  • Galactose

    Galactose: A sugar found in milk. Galactose is a disaccharide that is made up of two sugars, galactose and glucose, that are bound together.

  • Galactosemia

    Galactosemia: An inherited disorder of galactose metabolism that occurs in newborns and can result in damage to the liver, brain, kidneys, and other organs in infants due to the accumulation of galactose derivatives in the body. Individuals with galactosemia cannot tolerate any amount of human or animal milk intake. The symptoms of galactosemia resolve if […]


Disclaimer: Gage, Phineas definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.