Gene, transporter
Gene, transporter: A gene that allows drugs to enter cells or, in some cases, acts to keep them out. Transporter genes may account for discrepancies in the way drugs such as antidepressants, anticonvulsants, and chemotherapy agents work in different people. Also known as a drug-transporter gene.
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- Gene, Y-linked
Gene, Y-linked: A gene on the Y chromosome. (Y-linkage is analogous to X-linkage (the presence of a gene on the X chromosome) in that it says a gene is on one of the sex chromosomes.) It has often been said that little is known about genes that may be Y-linked. This is no longer true. […]
- Gene, zygotic lethal
Gene, zygotic lethal: A gene that is fatal for the zygote, the cell formed by the union of a sperm and an egg. The zygote would normally develop into an embryo, as instructed by the genetic material within the unified cell. However, a zygotic lethal gene kills prenatal development at its earliest point. A zygotic […]
- Gene-expression profiling
Gene-expression profiling: A genomic technique that based on the fact that only a fraction of the genes encoded in the genome of a cell are expressed by being transcribed into messenger RNA (mRNA). The complement of mRNAs in a cell largely dictates its complement of proteins. Consequently, gene expression is a major determinant of the […]
- General Clinical Research Center
General Clinical Research Center: (Abbreviated GCRC). See: Clinical Research Center.
- General paresis
General paresis: Progressive dementia and generalized paralysis due to chronic inflammation of the covering and substance of the brain (meningoencephalitis). General paresis is a part of late (tertiary) syphilis and is very rare today. It occurs a decade or more after the initial infection.