Excessive growth and height due to chronic overactivity of the pituitary gland (at the base of the brain). (Growth hormone is specifically made by the anterior pituitary gland.) In pituitary gigantism, there is secretion of too much growth hormone before the end of adolescence. People with pituitary gigantism can truly be giants. They can sometimes end up over 7 or 8 feet in height.
When too much growth hormone is secreted after adolescence, there cannot be an increase in height but a condition called acromegaly ensues. The cardinal manifestations of acromegaly include thickening of the skin, soft tissues, and bones of the hands and feet. These effects are insidious and very slowly progressive. Ultimately they cause considerable disability (aside from the need for larger rings, gloves, and shoes) including hoarseness, sleep apnea, joint pain, cardiovascular disease, hypertension, insulin resistance, visual impairment and severe headaches.
Pituitary gigantism and acromegaly may be caused by an adenoma of the pituitary (a tumor of the pituitary) or by other causes. Treatment is usually possible via medication or surgery. Inadequate treatment of pituitary gigantism and acromegaly is associated with increases in deaths from cardiovascular causes, cancer, and other causes.
- Gilbert syndrome
A common but harmless genetic condition in which UDP-glucuronosyltransferase, a liver enzyme that is essential to the disposal of bilirubin, is abnormal. Mutations in the same gene cause the Crigler-Najjar syndrome, which is a more severe and dangerous form of hyperbilirubinemia (high bilirubin in the blood). Also known as hyperbilirubinemia type 1.
Ginger, the rhizome of the plant Zingiber officinale, has been used as medicine in Asian, Indian, and Arabic herbal traditions since ancient times. In China, for example, ginger has been used to help digestion and treat stomach upset, diarrhea, and nausea for more than 2,000 years. Today, health care professionals may recommend ginger to help […]
Gum disease with inflammation of the gums. On inspection, the gums will appear red and puffy, and will usually bleed during tooth-brushing or dental examination. Treatment is by improved cleaning, with more-frequent and longer brushing and flossing, and/or the use of electronic tooth-cleaning equipment. Antiseptic mouthwashes may also be recommended. See also acute membranous gingivitis, […]
- Gingivitis, acute membranous
This is trench mouth, a progressive painful infection with ulceration, swelling and sloughing off of dead tissue from the mouth and throat due to the spread of infection from the gums. Certain germs (including fusiform bacteria and spirochetes) have been thought to be involved, but the full story behind this long- known disease is still […]
- Gingivitis, acute necrotizing ulcerative (ANUG)
This is trench mouth, a progressive painful infection with ulceration, swelling and sloughing off of dead tissue from the mouth and throat due to the spread of infection from the gums. Certain germs (including fusiform bacteria and spirochetes) have been thought to be involved, but the full story behind this long-known disease is still not […]