A test of carbohydrate metabolism that is used primarily in the diagnosis of type II diabetes and gestational diabetes. Abbreviated GTT. After the patient has fasted overnight, but before breakfast, a specific amount of glucose is given by mouth, and the blood levels of this sugar are measured every 30’60 minutes. The GTT result depends on a number of factors, including the ability of the intestines to absorb glucose, the power of the liver to take up and store glucose, the capacity of the pancreas to produce insulin, and the amount of ‘active’ insulin.
- Glucose tolerance, impaired
Impaired glucose tolerance.
- Glucose-6-phosphate dehydrogenase (G6PD)
Deficiency of G6PD is the commonest disease-causing enzyme defect in humans affecting an estimated 400 million people. The G6PD gene is on the X chromosome. Males with the enzyme deficiency develop anemia due to breakup of their red blood cells when they are exposed to oxidant drugs such as the antimalarial primaquine, the sulfonamide antibiotics […]
- Glucose, fasting blood
A method for learning how much glucose (sugar) there is in a blood sample taken after an overnight fast. The fasting blood glucose test is commonly used in the detection of diabetes mellitus. A blood sample is taken in a lab, doctor’s office, or hospital. The test is done in the morning before the person […]
- Glucuronosyltransferase, UDP-
Deficiency, UDP-glucuronosyltransferase, Gilbert’s Disease.
- Gerstmann-Straussler-Scheinker syndrome
A rare familial form of progressive dementia inherited in an autosomal dominant manner due to a mutant prion gene on chromosome 20pter-p12. Abbreviated GSS. Degeneration of the nervous system usually starts in the fourth or fifth decade of life with slowly developing dysarthria (difficulty speaking) and cerebellar ataxia (wobbliness) and later the progressive dementia become […]