Granuloma


A granuloma is one of a number of forms of localized nodular inflammation found in tissues. The fact that a granuloma is localized is important. So is its nodularity. Granulomas have a typical pattern when examined under a microscope.

Granulomas can be caused by a variety of biologic, chemical and physical irritants of tissue.

A calcified granuloma is a granuloma containing calcium deposits. Since it usually takes some time for calcium to be deposited in a granuloma, it is generally assumed that a calcified granuloma is an old granuloma. For example, a calcified granuloma in the lung may be due to tuberculosis contracted years earlier that is now dormant.

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  • Granuloma annulare

    This condition usually clears up by itself (it is “usually self-limited); it is not malignant (it is “benign”); we don’t have a clue as to what causes it (it is “of unknown etiology”); it affects the layer (the “dermis”) of the skin just below the outside layer (the epidermis). A granuloma is a localized nodular […]

  • Granuloma, calcified

    A granuloma that contains calcium deposits. Because it usually takes time for calcium to be deposited in a granuloma, a calcified granuloma is generally assumed to be an old granuloma.

  • Granuloma, fish bowl

    Localized nodular skin inflammation (small reddish raised areas of skin) caused by a bacterium called mycobacterium marinum. Fish bowl granuloma is typically acquired by occupational or recreational exposure to salt or fresh water, often resulting from minor trauma during caring for aquariums. The diagnosis is suggested by the history of exposure and confirmed by culturing […]

  • Granuloma, swimming pool

    Localized nodular skin inflammation (small reddish raised areas of skin) caused by a bacterium called Mycobacterium marinum. Swimming pool granuloma is typically acquired by occupational or recreational exposure to salt or fresh water, often resulting from minor trauma during caring for aquariums. The diagnosis is suggested by the history of exposure and confirmed by culturing […]

  • Granulomatosis, allergic

    A disease (also more commonly called the Churg-Straus syndrome) characterized by inflammation of the blood vessels in persons with a history of asthma or allergy. The symptoms of the Churg-Strauss syndrome include fatigue, weight loss, inflammation of the nasal passages, asthma symptoms, numbness, and weakness. The ultimate test for the diagnosis of Churg-Straus syndrome is […]


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