Granulomatous colitis


Involvement of the large intestine (colon) only is called Crohn’s colitis or granulomatous colitis, while involvement of the small intestine alone is called Crohn’s enteritis. The most common part of the small intestine to be affected by Crohn’s disease is the last portion, called the ileum. Active disease in this area is termed Crohn’s ileitis. When both the small intestine and the large intestine are involved, the condition is called Crohn’s enterocolitis (or ileocolitis). Other descriptive terms may be used as well.

Abdominal pain, diarrhea, vomiting, fever, and weight loss can be symptoms. Crohn’s disease can be associated with reddish tender skin nodules, and inflammation of the joints, spine, eyes, and liver. Diagnosis is commonly made by x-ray or colonoscopy. Treatment includes medications that are anti-inflammatories, immune suppressors, or antibiotics. Surgery can be necessary in severe cases.

Crohn’s disease is an area of active research around the world and new treatment approaches are being investigated which have promise to improve the lives of affected patients.

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