Histiocytosis X


Now called Langerhans cell histiocytosis. This disease is subclassified into eosinophilic granuloma, Letterer Siwe disease, and Hand-Schuller-Christian disease.

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  • Histiocytosis, Hand-Schuller-Christian

    A disease in which histiocytes start to multiply and attack the tissues or organs of the patient. The disease usually affects children age 2 to 5, less often older children and adults. The most frequent sites of bony involvement are the flat bones of the skull, ribs, pelvis, and scapula (wing bone). Chronic otitis media […]

  • Histiocytosis, Letterer Siwe

    A severe disease in which histiocytes start to multiply and attack the tissues or organs of the patient starting in infancy with a scaly, sometimes itchy rash on the scalp, ears, abdomen, and creases of the neck and face. Raw skin may provide a portal of entry for germs, leading to sepsis (bloodstream infection). There […]

  • Histiocytosis, Langerhans cell

    Histiocytosis in which the active histiocytes normally occur in the skin. See histiocytosis.

  • Histiocytosis, lipid

    A form of histiocytosis that affects lipid (fat) storage. Also known as Niemann- Pick disease, Erdheim-Chester disease.

  • Histiocytosis, malignant

    A term sometimes used to refer to a group of tumors including monocyte-related leukemias (for example, acute monocytic leukemia, acute myelomonocytic leukemia), extramedullary monocytic tumor, and histiocytic sarcoma. Treatment is by radiation and chemotherapy, and in some cases bone-marrow transplantation. See also histiocytosis.


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