Immune tolerance


Prior contact with the same antigen in fetal life or in the newborn period when the immune system is not yet mature;
Prior contact with the antigen in extremely high or low doses;
Exposure to radiation, chemotherapy drugs, or other agents that impair the immune system;
Heritable diseases of the immune system;
Acquired diseases of the immune system such as HIV/AIDS.

Immune tolerance can be defined as a state in which a T cell can no longer respond to antigen. The T cell “tolerates” the antigen.

Read Also:

  • Immunity

    The condition of being immune. Immunity can be innate’for example, humans are innately immune to canine distemper’or conferred by a previous infection or immunization.

  • Immunity, active

    The production of antibodies against a specific agent by the immune system. Active immunity can be acquired in two ways, by contracting an infectious disease such as chickenpox or by receiving a vaccination such as against chickenpox. Active immunity is usually permanent. The individual is protected from the disease all their life. Active immunity is […]

  • Immunization

    Vaccination. Immunizations work by stimulating the immune system, the natural disease-fighting system of the body. The healthy immune system is able to recognize invading bacteria and viruses and produce substances (antibodies) to destroy or disable them. Immunizations prepare the immune system to ward off a disease. To immunize against viral diseases, the virus used in […]

  • Immunization, anthrax

    A series of six shots over six months and booster shots annually, the anthrax vaccine now in use in the USA was first developed in the 1950s and approved by the Food and Drug Administration for general use in 1970. It is produced by the Michigan Biologic Products Institute of Michigan’s Department of Health and […]

  • Immunization, chickenpox

    See Chickenpox immunization.


Disclaimer: Immune tolerance definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.