An isotope of the chemical element iodine that is radioactive. Radioactive iodine is used in diagnostic tests as well as in radiotherapy of an hyperactive thyroid gland (hyperthyroidism), most often due to Graves disease.
For hyperthyroidism, Radioactive iodine is administered in capsule form on a one- time basis. It directly radiates thyroid tissues, thereby destroying them. It takes 8-12 weeks for the thyroid to become euthyroid (normal) after treatment.
The majority of patients undergoing this treatment with radioactive iodine eventually become hypothyroid, which is easily treated using thyroid hormones (levothyroxine).
Radioactive iodine should not be used during pregnancy or breast feeding.
Radioactive iodine is the preferred initial therapy for the hyperthyroidism of Graves disease in North America while antithyroid drugs are used as the first line of treatment in most of the rest of the world. Radioactive iodine is also known as radioiodine.
- Ion channel
A protein that acts as a pore in a cell membrane and permits the selective passage of ions (such as potassium ions, sodium ions, and calcium ions), by means of which electrical current passes in and out of the cell. Ion channels also serve many other critically important functions including chemical signalling, transcellular transport, regulation […]
A transdermal delivery system in which a substance bearing a charge is propelled through the skin by a low electrical current. This method can be used to drive a drug across the skin barrier.
- IOP (intraocular pressure)
The pressure created by the continual renewal of fluids within the eye. The normal IOP varies among individuals. The intraocular pressure is increased in glaucoma. In acute angle-closure glaucoma, the intraocular pressure rises rapidly because the iris blocks the angle in the front of the eye where the anterior chamber fluid normally drains out. In […]
A naturally occurring substance with multiple properties including the ability to cause vomiting (emesis). Ipecac is derived from dried roots of a bush called Uragoga ipecacuanha that is native to Brazil. In the past, a sizable proportion of poison exposures in the U.S. were treated with ipecac. This practice has dropped off and some experts […]
On the same side, as opposed to contralateral. For example, a tumor involving the right side of the brain may affect vision ipsilaterally’that is, in the right eye.