Or Jak3. An enzyme found only in cells in the immune system that is critical for the cell signaling process resulting in the development of white blood cells. Mutation of the gene encoding JAK3 is responsible for a form of severe combined immunodeficiency (SCID). JAK stands for Janus kinase or Just Another Kinase.
- JAK3 inhibitor
A drug that inhibits the enzyme JAK3 (which is found only in immune cells) and acts as an immunosuppressant.
- Jakob's disease
Better known as Creutzfeldt-Jakob disease (CJD), a dementing disease of the brain. It is believed due to an unconventional, transmissible agent (a prion). Symptoms of CJD include forgetfulness, nervousness, jerky trembling hand movements, unsteady gait, muscle spasms, chronic dementia, balance disorder, and loss of facial expression. CJD is classified as a spongiform encephalopathy. Most cases […]
- Jakob-Creutzfeldt disease
A degenerative disease of the brain that causes dementia and, eventually, death. It is believed to be caused by an unconventional microbe called a prion, rather than by bacteria or a virus. Abbreviated CJD. Symptoms of CJD include forgetfulness, nervousness, trembling hand movements, unsteady gait, muscle spasms, chronic dementia, balance disorder, and loss of facial […]
- American Medical Association
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“To promote the science and art of medicine and the betterment of the public health.” JAMA carries original, generally well-documented, peer-reviewed medical articles on a diversity of clinical as well as laboratory topics.