Acute fatty liver of pregnancy (AFLP) has been found to be associated in some cases with an abnormality of fatty-acid metabolism. This abnormality is a deficiency of the enzyme long-chain-3-hydroxyacyl-CoA dehydrogenase (LCHAD).
The mother (and father) have 50% of normal LCHAD activity and the fetus has no LCHAD activity.
The metabolic disease in the baby’s liver apparently causes the fatty liver disease in the mother. In cases of AFLP due to LCHAD deficiency, there is a 25% (or greater) risk of AFLP in each pregnancy.
- Long-term care facility
A facility that provides rehabilitative, restorative, and/or ongoing skilled nursing care to patients or residents in need of assistance with activities of daily living. Long-term care facilities include nursing homes, rehabilitation facilities, inpatient behavioral health facilities, and long-term chronic care hospitals.
- Long-term memory
A system for permanently storing, managing, and retrieving information for later use. Items of information stored as long-term memory may be available for a lifetime. Long-term memory is in contrast to short-term memory.
Lifespan. Increased longevity means a longer life.
Along the length of something; running lengthwise or, by extension, over the course of time.
- Longitudinal study
A study done over the passage of time. For example, a longitudinal study of children with Down syndrome might involve the study of 100 children with this condition from birth to 10 years of age. Longitudinal study is the opposite of cross-sectional (synchronic) study. Also known as diachronic study.