An abnormally large head. The opposite of macrocephaly is microcephaly. Macrocephaly can be a normal variant or be a sign of pressure within the growing head during childhood, such as from hydrocephalus.
- Macrocephaly, multiple lipomas, and hemangiomas
50 chance of transmitting the Bannayan gene to each of their children. The gene is on chromosome 10q23.3 and the mutation is now known to involve the phosphatase and tensin homolog gene called PTEN. A different mutation in PTEN causes Cowden disease which is a syndrome of multiple hamartomas (malformations resembling tumors composed of mature […]
A condition in which the external sex organs are prematurely or abnormally enlarged. Macrogenitosomia is associated with hormonal disorders that may also create changes in the internal sex organs.
A condition in which the blood contains high levels of large proteins. If the levels are too high the blood may become too thick or viscous and thus become too thick to flow through small blood vessels. The large protein is an antibody called macroglobulin or IgM. One type of macroglobulinemia is Waldenström’s macroglobulinemia, a […]
- Macroglobulinemia, Waldenstrom
An abnormally large tongue. Macroglossia is sometimes said to be associated with Down syndrome, but in that disorder the tongue is actually large only in relationship to a smaller-than-normal mouth cavity.