Map, physical
A map of the locations of identifiable landmarks on chromosomes. Physical distance is measured in base pairs. The physical map differs from the genetic map which is based purely on genetic linkage data. In the human genome, the lowest-resolution physical map is the banding patterns of the 24 different chromosomes. The highest-resolution physical map is the complete nucleotide sequence of all chromosomes, a future goal.
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Cogan corneal dystrophy. It is also known (to add to the confusion) as microcystic corneal dystrophy.
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A hereditary disease that is due to deficiency of an enzyme involved in amino acid metabolism, characterized by urine that smells like maple syrup. In maple syrup urine disease, the three branched-chain amino acids (leucine, isoleucine, and valine) cannot be metabolized (processed), and they build up in the blood, causing problems with brain function and […]
- Mapping, gene
The charting of the positions of genes on a DNA molecule or chromosome and the distance, in linkage units or physical units, between genes.
- Marasmus
Wasting away, as occurs with children who have kwashiorkor. Also called cachexia, is usually a result of protein and calorie deficiency.
- Marfan syndrome
An inherited disorder of connective tissue that is characterized by abnormalities of the eyes, skeleton, and cardiovascular system. Nearsightedness (myopia) is the most common eye feature in Marfan syndrome. Displacement of the lens from the center of the pupil occurs in more than half of patients. Patients with Marfan syndrome have an increased risk for […]