A mother with the genetic disease phenylketonuria (PKU) whose high blood levels of phenylalanine (phe) are dangerous to a developing fetus. High phe is a teratogen. It can damage a baby before birth.
Women with PKU who are off the special PKU diet should restart back it, ideally prior to conception. During pregnancy they must be on the diet and have their blood phe levels carefully monitored. If the maternal PKU is not controlled, the baby (who does not have PKU) is at risk for congenital heart disease, growth retardation, microcephaly (abnormally small head), and mental retardation.
- Maternal serum alpha-fetoprotein (MSAFP)
High with open neural tube defects such as anencephaly and spina bifida (meningomyelocele); and Low with Down syndrome (trisomy 21, an extra chromosome number 21). Alpha-fetoprotein production is essentially zero after a year of age. However, it increases again under the stimulus of some liver diseases. It may, for example, be produced by viral hepatitis […]
1. Literally, relating to a maternal aunt. 2. Figuratively, suggestive of an aunt on either side of the family. 3 In medical genetics, pertaining to an aunt. An materteral relationship is the genetic relationship between aunts and their nieces and nephews. Materteral is synonymous with materterine. From the Latin matertera meaning maternal aunt, from mater […]
- Mathematics disorder
A condition characterized by math skills that are significantly below normal, given the person’s age, intelligence, and education. A mathematics disorder can include problems writing or printing numbers, counting, adding and subtracting, interpreting simple mathematical signs such as +, -, x, and / and learning terms that include numbers. Mathematics disorder often comes to attention […]
the process of surgically or chemically destroying all or part of the base nail portion called the nail matrix. Complete destruction of the nail matrix results in permanent loss of that portion of the nail. Once the nail matrix is fully removed or destroyed, a new nail plate cannot ever be regenerated. This surgical procedure […]
- Matter, gray
The cortex of the brain, which contains nerve cell bodies. The gray matter is so named because it is darker than the white matter, the part of the brain that contains myelinated nerve fibers.