Monocyte chemotactic protein-1, a member of the small inducible gene (SIG) family, plays a role in the recruitment of monocytes to sites of injury and infection. The gene for MCP1 is on chromosome 17 in region 17q11.2-q12.
MPC1 has been found in the joints of people with rheumatoid arthritis where may serve to recruit macrophages and perpetuate the inflammation in the joints. MPC1 has also been found elevated in the urine of people with lupus as a sign warning of inflammation of the kidney.
MCP1 has also been called small inducible cytokine A2 (SCYA2) and monocyte chemotactic and activating factor (MCAF).
Membrane cofactor protein. A ubiquitous protein on the surface of cells that regulates complement and is involved in the attachment and ingestion of foreign particles by neutrophils and macrophages. The gene for MCP is on chromosome 1q32.
Abbreviation standing for mixed connective tissue disease.
Abbreviation for mean cell volume, the average volume of a red blood cell. This is a calculated value derived from the hematocrit and the red cell count (The hematocrit is the ratio of the volume of red cells to the volume of whole blood while the red cell count is the number of red blood […]
Abbreviation for the Latin Medicinae Doctor, Doctor of Medicine.
Multidetector computed tomography.