Methylation
1. In chemistry, the addition of a methyl group to a molecule. 2. On a protein level, the addition of a methyl group or groups to the amino acid arginine or lysine in a protein. 3. On a DNA level, the addition of a methyl group to a cytosine residue to convert it to 5-methylcytosine. Methylation of DNA occurs at CpG sites, where cytosine (C) lies next to guanine (G). The CpG sites are in regions near the promoters of a genes. These regions are known as CpG islands. The state of methylation of CpG islands is critical to both gene activity and gene expression.
Read Also:
- Methylmalonicaciduria
methylmalonicaciduria, long chain ketonuria, and intermittent hyperglycinemia.) Some but not all patients with methylmalonicaciduria respond to vitamin B12. An enzyme called methylmalonyl-CoA mutase is defective in the disease. This enzyme requires the presence of adenosylcobalamin, a form of vitamin B12. The metabolic block in methylmalonic acidemia occurs at methylmalonyl-CoA mutase and can be caused by […]
- Metrorrhagia
Menometrorrhagia; Menorrhagia.
- Methylmercury
Mercury poisoning; Minamata disease.
- Meuse fever
184-189, 1999). The organism (B. quintana) that causes trench fever also has been found responsible for a disease called bacillary angiomatosis in people infected with HIV and for infection of the heart and great vessels (endocarditis) with bloodstream infection. Trench fever is also called Wolhynia fever, shin bone fever, quintan fever, five-day fever, His’ disease, […]
- Membrane-associated neutral endopeptidase
Metallomembrane endopeptidase.