Mutagen
Something that is capable of mutating DNA. Among the known mutagens are radiation, certain chemicals, and some viruses.
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- MPH
Master of public health, a degree designating successful training in analyzing past, present, and future public health issues.
- MP
Abbreviation for mercaptopurine and molecular pathology.
- Mutation, germline
A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single-cell stage. (This is also termed gonadal mosaicism) When transmitted to a child, a germline mutation is incorporated in every cell of their body. Germline […]
- Mutation, null
A mutation (a change) in a gene that leads to its not being transcribed into RNA and/or translated into a functional protein product. For example, a null mutation in a gene that usually encodes a specific enzyme leads to the production of a nonfunctional enzyme or no enzyme at all.
- Mutation, point
A single nucleotide base change in the DNA. A point mutation may consist of the loss of a nucleotide, the insertion of an additional nucleotide, or the substitution of one nucleotide for another. The first point mutation discovered in humans involved the substitution of one nucleotide for another. It was in sickle hemoglobin, the molecular […]