An enzyme in leukocytes (white blood cells) that is linked to inflammation and cardiovascular disease. An elevated blood level of the enzyme predicts the early risk of myocardial infarction (heart attack). Abbreviated MPO.
- Myeloperoxidase deficiency
Deficiency of the enzyme myeloperoxidase which may predispose to severe fungal infections. The enzyme is critical to the oxygen-dependent killing of bacteria by leukocytes (white blood cells).
Referring to the proliferation of the bone marrow cells that give rise to red blood cells, granulocytes (a type of white blood cells), and/or platelets (crucial to blood clotting). The term myeloproliferative is in contrast to lymphoproliferative which refers to proliferation of lymphoid cells and reticuloendothelial cells such as macrophages. Both terms — myeloproliferative and […]
A base excision repair gene responsible for an hereditary colon cancer syndrome. MYH is located on the short (p) arm of chromosome 1 in region 1p34.3-p32.1. MYH encodes an enzyme that removes the base adenine from mispairs (with 8-oxoguanine) that arise during the replication of oxidized DNA. MYH is also known as MUTYH. A substantial […]
- Myeloproliferative disorders
Malignant diseases of certain bone marrow cells including those that give rise to the red blood cells, the granulocytes (types of white blood cells), and the platelets (crucial to blood clotting). The myeloproliferative disorders include myelophthisic anemia, erythroblastic leukemia, leukemoid reaction, myelofibrosis, myeloid metaplasia, polycythemia vera, and thrombocytosis. The myeloproliferative disorders are in contrast to […]
- Myo- (prefix)
A prefix denoting a relationship to muscle. Myo- enters into many words and terms in medicine including cardiomyopathy, dermatomyositis, electromyography, leiomyoma, myocardial infarction, myocarditis, myocardium, myoclonic, myocyte, myopathy, myoglobin, myometrium, myotonia, myotonic dystrophy, and polymyositis.