Myeloproliferative
Referring to the proliferation of the bone marrow cells that give rise to red blood cells, granulocytes (a type of white blood cells), and/or platelets (crucial to blood clotting). The term myeloproliferative is in contrast to lymphoproliferative which refers to proliferation of lymphoid cells and reticuloendothelial cells such as macrophages. Both terms — myeloproliferative and lymphoproliferative — can be applied to conditions that are entirely benign, premalignant, or frankly malignant.
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- MYH
A base excision repair gene responsible for an hereditary colon cancer syndrome. MYH is located on the short (p) arm of chromosome 1 in region 1p34.3-p32.1. MYH encodes an enzyme that removes the base adenine from mispairs (with 8-oxoguanine) that arise during the replication of oxidized DNA. MYH is also known as MUTYH. A substantial […]
- Myeloproliferative disorders
Malignant diseases of certain bone marrow cells including those that give rise to the red blood cells, the granulocytes (types of white blood cells), and the platelets (crucial to blood clotting). The myeloproliferative disorders include myelophthisic anemia, erythroblastic leukemia, leukemoid reaction, myelofibrosis, myeloid metaplasia, polycythemia vera, and thrombocytosis. The myeloproliferative disorders are in contrast to […]
- Myo- (prefix)
A prefix denoting a relationship to muscle. Myo- enters into many words and terms in medicine including cardiomyopathy, dermatomyositis, electromyography, leiomyoma, myocardial infarction, myocarditis, myocardium, myoclonic, myocyte, myopathy, myoglobin, myometrium, myotonia, myotonic dystrophy, and polymyositis.
- Myocardial bridge
Literally a bridging of heart muscle over one of the major arteries to the heart (usually the left anterior descending artery). The heart has formed in this abnormal design from birth, whereby the artery is actually ‘tunneled’ through a part of the heart muscle.
- Myocardial infarction
A heart attack. Abbreviated MI. The term “myocardial infarction” focuses on the myocardium (the heart muscle) and the changes that occur in it due to the sudden deprivation of circulating blood. The main change is necrosis (death) of myocardial tissue. The word “infarction” comes from the Latin “infarcire” meaning “to plug up or cram.” It […]