Onychoosteodysplasia
Iliac horns,
Abnormality of the elbows interfering with full range of motion (pronation and supination), and
Kidney disease resembling glomerulonephritis, which is often mild but can be progressive and lead to renal failure.
Nail-patella syndrome is inherited as dominant gene. This means that the disease can be transmitted by an affected parent. The nail-patella gene locus was found linked genetically to the ABO blood group locus in 1965 and is now known to be in chromosome region 9q34.
The disorder is also known as Fong disease and Turner-Kieser syndrome. Dr. Fong in 1946 did an intravenous pyelography (IVP) and on X-ray saw the ‘iliac horns’ (symmetrical bilateral central posterior iliac processes) which are a characteristic feature of the disease. The Turner-Kieser syndrome came about because Henry H. Turner (1892-1970), an Oklahoma endocrinologist, described 2 families with the disease in 1933. His name is more commonly associated with the Turner syndrome that affects about 1 in 2000 newborn girls and is due a missing or abnormal X chromosome.
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The rarest form of fungus infection of the finger or toenail. (Fungus infection of the finger or toenail is also called onychomycosis.) The infection begins in the nail fold (the portion of the nail opposite the tip of the finger). Proximal white subungual onychomycosis is typically associated with HIV infection (AIDS), though it can follow […]
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Fungus infection of the nail bed under the fingernails or toenails. Onychomycosis makes the nails look white and opaque, thickened, and brittle. It usually produces no symptoms other than a cosmetic problem. Treatment includes avoiding artificial nails, using safer application techniques and only new artificial nails, and using topical and oral antifungal medications. Also known […]
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Having to do with bone, consisting of bone, or resembling bone.
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Any small bone, such as the tiny bones within the human ear.
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The process of creating bone, that is of transforming cartilage (or fibrous tissue) into bone. The human skeleton initially consists largely of cartilage which is relatively soft and is gradually transformed into hard bone during infant and child development. The verb corresponding to “ossification” is “ossify.” Cartilage becomes ossified as it is converted into bone. […]