Osteoclasis
The surgical destruction of bone tissue. Osteoclasis is performed to reconstruct a bone that is malformed, often a broken bone that healed improperly. The bone is broken and then reshaped with the aid of metal pins, casting, and bracing.
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- Osteoclast
A cell that nibbles at and breaks down bone and is responsible for bone resorption. Osteoclasts are large multinucleate cells (cells with more than one nucleus) that differentiate from another type of cell called a macrophage. In normal bone, bone formation and bone resorption are closely coupled processes involved in the normal remodeling of bone. […]
- Osteoclastoma
A tumor of bone characterized by massive destruction of the end (epiphysis) of a long bone. The site most commonly struck by this tumor is the knee ? the far end of the femur and the near end of the tibia. The tumor is often coated by new bony growth and may grow aggressively. It […]
- Osteodystrophy
A bone disorder that adversely affects bone growth. See also renal osteodystrophy.
- Osteodystrophy, renal
A bone disorder that adversely affects bone growth and is caused by chronic kidney failure (renal disease). Osteo?dystrophy can require treatment with vitamin D. Also known as kidney osteodystrophy.
- Osteogenesis imperfecta
A group of inherited connective tissue diseases, all of which result from mutations that affect collagen in connective tissue in the body, and all of which result in fragile bones. The best known types of osteogenesis imperfecta are types I and II. Also known as brittle bone disease.