Pachyonychia congenita, type 1


“The nail plates of all the fingers and toes are extremely thickened, and so hard that they cannot be cut with a scissors; the father has to trim them with a hammer and chisel.”

Read Also:

  • Pacifier

    An artificial nipple, usually made of plastic, upon which an infant can suck to gain some solace and quiet down. A pacifier is called by other names in other countries including a “dummy” in the U.K. Pacifiers have been claimed to cause early weaning. However, a study (JAMA, July 18, 2001) was done of women […]

  • Paediatrics

    Pediatrics in Great Britain.

  • Page kidney

    Chronic longstanding compression of the kidney resulting in hypertension. The kidney is compressed, most often, by a post-traumatic subcapsular hematoma (a collection of blood beneath the capsule surrounding the kidney) or, less often, by a cyst or tumor pressing on the renal parenchyma (substance of the kidney). The compression decreases blood flow to the kidney […]

  • Paget disease

    Arthritis — Long bones in the leg may bow, distorting alignment and increasing pressure on nearby joints. In addition, Pagetic bone may enlarge, causing joint surfaces to undergo excessive wear and tear. In these cases, pain may be due to a combination of Paget’s disease and osteoarthritis. Hearing — Loss of hearing in one or […]

  • Paget disease of the breast

    The combination of scaly skin changes of the nipple resembling eczema and an underlying cancer of the breast. The nipple is inflamed because of the presence of Paget’s cells. These large irregular cells are themselves not cancerous, but they are almost always associated with a cancer in the breast. The reason for the Paget’s cells […]


Disclaimer: Pachyonychia congenita, type 1 definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.