Pancreatic insufficiency


Not enough of the digestive enzymes normally secreted by the pancreas into the intestine. Pancreatic insufficiency is a hallmark of cystic fibrosis.

The pancreas is a spongy, tube-shaped organ about 6 inches long. It is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the duodenum, the upper end of the small intestine. The narrow end of the pancreas, called the tail, extends to the left side of the body.

The pancreas makes pancreatic juices and hormones, including insulin. Pancreatic juices, also called enzymes, help digest food in the small intestine. Insulin controls the amount of sugar in the blood. Both enzymes and hormones are needed to keep the body working right.

As pancreatic juices are made, they flow into the main pancreatic duct. This duct joins the common bile duct, which connects the pancreas to the liver and the gallbladder. The common bile duct, which carries bile (a fluid that helps digest fat), connects to the small intestine near the stomach.

Read Also:

  • Pancreatic juices

    Fluids made by the pancreas that contain digestive enzymes. The pancreas is a spongy, tube-shaped organ about 6 inches long. It is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the duodenum, the upper end of […]

  • Pancreatitis

    Inflammation of the pancreas. Of the many causes of pancreatitis, the most common are alcohol consumption and gallstones. Other causes include medications (azathioprine, estrogen, thiazides, metronidazole, valproic acid, and tetracycline), trauma, abdominal surgery, abnormalities of the pancreas and intestine, and infections such as mumps. Acute pancreatitis usually begins with pain in the upper abdomen that […]

  • Pancytopenia

    A shortage of all types of blood cells. Pancytopenia can be caused by a side effect of many medications (such as azathioprine, methotrexate, and others) or diseases (such as lupus and bone marrow disorders). Treatment is directed toward the underlying cause and may be supplemented by medications that stimulate the bone marrow.

  • PANDAS

    An acronym for Pediatric Autoimmune Disorders Associated with Strep. PANDAS is the sudden onset of symptoms like those of obsessive-compulsive disorder or Tourette syndrome following infection with streptococcus bacteria, caused by an autoimmune reaction that affects the basal ganglia in the brain. If tics are seen, they may or may not be choreaform like those […]

  • Pandemic

    An epidemic affects more than the expected number of cases of disease occurring in a community or region during a given period of time. A sudden severe outbreak within a region or a group as, for example, AIDS in Africa or AIDS in intravenous drug users. An endemic is present in a community at all […]


Disclaimer: Pancreatic insufficiency definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.