Suffix meaning paralysis or a stroke. As in cardioplegia (paralysis of the heart), hemiplegia (paralysis of one side of the body), paraplegia (paralysis of the legs), and quadriplegia (paralysis of all four extremities). From the Greek plege meaning a blow or stroke.
Producing or having multiple effects from a single gene. For example, the Marfan gene is pleiotropic, potentially causing such diverse effects as long fingers and toes (arachnodactyly), dislocation of the lens of the eye, and dissecting aneurysm of the aorta.
- Pleiotropic cytokine
cytokine that affects the activity of multiple cell types. A cytokine is a small protein that has a specific effect on the interactions between cells, on communications between cells, or on the behavior of cells.
Many-formed. For example, a pleomorphic tumor would be a growth that is composed of different types of tissues. Also known as protean.
An excess in the number of parts or in the size of a growth. Pleonasm comes from a Greek word (pleonasmos) meaning exaggeration or redundancy. A pleonasm in language is also a redundancy. It is the use of more words than those necessary to denote mere sense as, for example, in “a false lie.”
Florid, red-faced. Persons with polycythemia vera commonly have a plethoric facial appearance.