Polyploid
Having three or more full sets of chromosomes. For example, a polyploid brain tumor cell might have 69 or 92 chromosomes.
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- Polypsis of the colon
Multiple polyps with a high malignant potential in the large bowel. This hereditary condition is also known as polypsis coli and Familial Adenomatous Polyposis (FAP).
- Polysomnography
Continuous recording of specific physiologic variables during sleep. Polysomnography typically records brain wave changes (electroencephalogram), eye movements (electrooculogram), muscle tone (electromyogram), respiration, electrocardiogram (EKG), and leg movements.
- Polyubiquitination
The binding of many ubiquitin molecules to the same target protein. Polyubiquitination of proteins is the triggering signal that leads to degradation of the protein in the proteasome. It is polyubiquitination that constitutes the “kiss of death” for the protein.
- Polyuria
Nephrogenic diabetes insipidus — a genetic disease Polycystic kidney disease — another genetic disease Sickle cell disease Pyelonephritis — infection of kidneys Amyloidosis — deposits of a substance called amyloid in the kidney Sjogren syndrome, and Myeloma. Certain drugs such as the mood stabilizer lithium (Lithobid, Eskalith) and the antibiotic demeclocycline (Declomycin) can also lead […]
- Pompe disease
An inherited deficiency of the enzyme alpha-glucosidase which helps the body break down glycogen, a complex carbohydrate that is converted to glucose for energy. Without the enzyme, glycogen builds up in the heart and other muscles, causing extensive damage. There are several different forms of Pompe disease which vary in severity. Pompe disease is inherited […]