Polysomnography
Continuous recording of specific physiologic variables during sleep. Polysomnography typically records brain wave changes (electroencephalogram), eye movements (electrooculogram), muscle tone (electromyogram), respiration, electrocardiogram (EKG), and leg movements.
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- Polyubiquitination
The binding of many ubiquitin molecules to the same target protein. Polyubiquitination of proteins is the triggering signal that leads to degradation of the protein in the proteasome. It is polyubiquitination that constitutes the “kiss of death” for the protein.
- Polyuria
Nephrogenic diabetes insipidus — a genetic disease Polycystic kidney disease — another genetic disease Sickle cell disease Pyelonephritis — infection of kidneys Amyloidosis — deposits of a substance called amyloid in the kidney Sjogren syndrome, and Myeloma. Certain drugs such as the mood stabilizer lithium (Lithobid, Eskalith) and the antibiotic demeclocycline (Declomycin) can also lead […]
- Pompe disease
An inherited deficiency of the enzyme alpha-glucosidase which helps the body break down glycogen, a complex carbohydrate that is converted to glucose for energy. Without the enzyme, glycogen builds up in the heart and other muscles, causing extensive damage. There are several different forms of Pompe disease which vary in severity. Pompe disease is inherited […]
- PON
The symbol for the enzyme called paraoxonase.
- Pons
A specific section of the brain formed by the rounded prominence on the front surface of the brainstem. (The brainstem is the lowest part of the brain that merges with the spinal cord; it consists of a structure called the medulla oblongata, the midbrain and the pons.) Cranial nerves V, VI, VII and VIII take […]