Prion


A small proteinaceous infectious disease-causing agent that is believed to be the smallest infectious particle. A prion is neither bacterial nor fungal nor viral and contains no genetic material. Prions have been held responsible for a number of degenerative brain diseases, including mad cow disease, Creutzfeldt-Jakob disease, fatal familial insomnia, kuru, and an unusual form of hereditary dementia known as Gertsmann-Straeussler-Scheinker disease.

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    Gerstmann-Straussler-Scheinker syndrome.

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    A rare gene mutation that is usually found only in a single family or a small population. A private mutation occurs and is passed to a few family members, but not to future generations.

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  • Pro-

    A combining form (from both Greek and Latin) with many meanings including “before, in front of, preceding, on behalf of, in place of, and the same as.” Used as a word, pro of course means professional and, in medicine, it is short for prothrombin.


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