One of the vitamin B6 group (which also includes pyridoxal and pyridoxamine) that is transformed in the body to pyridoxal phosphate, which functions as a coenzyme, a substance that enhances the action of an enzyme and thereby helps catalyze and speed a biochemical reaction. (A number of vitamins serve as coenzymes.)
The vitamin B6 group is especially important to the function of the central nervous system, skin, and blood. Vitamin B6 is involved in the formation of red blood cells since pyridoxal phosphate is the rate-limiting substance in making heme, a component of hemoglobin, the key oxygen-carrying pigment in red blood cells.
The diet rarely lacks vitamin B6. Most foods contain it. However, deficiency of vitamin B6 within the body may occur due to poor absorption of it from the intestine or inactivation of it by some drugs (e.g., anticonvulsants, corticosteroids, estrogens, isoniazid, and penicillamine). Other causes of vitamin B6 include alcoholism and conditions such as hyperthyroidism and diabetes that increase the metabolic demand, creating a relative shortage of vitamin B6.
Vitamin B6 deficiency causes convulsions in infants and anemia in adults. An outbreak of convulsions in infants followed the inadvertent destruction of vitamin B6 in infant formulas. Several genetic syndromes also involve problems with vitamin B6.
One of the two classes of bases in DNA and RNA. The pyrimidine bases are thymine (T) and cytosine (C) in DNA and cytosine (C) and uracil (U) in RNA.
- Pyrophosphate arthropathy
Joint damage due to deposition of calcium pyrophosphate. Pyrophosphate arthropathy most commonly affects the knees, wrists and knuckles and tends to be symmetrical.
A technical term for what is popularly called heartburn, a burning sensation in the upper abdomen. In many languages there is a technical term such as pyrosis and a popular term for the same phenomenon. For example, pyrosis is popularly known in French as br�lure epigastrique and in Spanish as ardor de est�mago. Pyrosis is […]
(Born c. 580 B.C.E.) Greek philosopher and mathematician who promoted health through a special vegetarian diet.
Pus in the urine. Pyuria is a sign of inflammation, often related to infection.