Sclerosis, multiple
A disease that is characterized by loss of myelin (demyelinization). Abbreviated MS. Myelin, the coating of nerve fibers, is composed of lipids (fats) and protein. It serves as insulation and permits efficient nerve fiber conduction. In MS, demyelinization usually affects white matter in the brain, but sometimes it extends into the gray matter. When myelin is damaged, nerve fiber conduction is faulty or absent, and nerve cell death may occur. Impaired bodily functions or altered sensations associated with those demyelinated nerve fibers give rise to the symptoms of MS, which range from numbness to paralysis and blindness. People with MS experience attacks of symptoms that may last days, months, or longer. For many patients, the disease is progressive and leads to disablement, although some cases enter long, perhaps even permanent, remission. The cause of MS is unknown, although viral activity is suspected. Most patients are diagnosed between the ages of 20 and 40. Until recently, treatment had focused on preventing attacks. Steroids, interferon, and medications to treat specific symptoms (such as fatigue, depression, and vertigo) are standard, along with lifestyle changes to avoid stress and other triggers. New treatment options involve immune system modulation or support.
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- Scoliosis
Lateral (sideways) curving of the spine. The degree of scoliosis may range from mild to severe. Of every 1,000 children, 3 to 5 develop spinal curvature that is considered severe enough to need treatment. Adolescent idiopathic (of unknown cause) scoliosis is the most common type and appears after the age of 10, commonly in teens. […]
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Lateral (sideways) curving of the spine that is neither present at birth nor results from a condition that is present at birth.
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