Sequence, finished DNA
A DNA sequence in which the bases are identified to an accuracy of no more than 1 error in 10,000 and are placed in the right order and orientation along a chromosome with almost no gaps. A finished sequence is as opposed to a draft DNA sequence.
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- Sequence, intervening
An intervening sequence is the part of a gene that is initially transcribed from the DNA into RNA (specifically, into the primary RNA transcript) but then is excised (removed) from it when the so-called exxon sequences on either side of it are spliced together. Intervening sequences intervene between the exxons. Intervening sequences are also called […]
- Sequence, regulatory
A sequence of bases in DNA that controls gene expression.
- Sequencing
Determining the order of nucleotides (base sequences) in a DNA or RNA molecule, or determining the order of amino acids in a protein.
- Sequester
1. In medicine, to set apart, detach or separate a small portion of tissue from the rest. May be naturally occurring or iatrogenic. 2. In bone, for a piece of dead bone to separate from the sound bone. 3. In biochemistry, to isolate a constituent of a system by chelation or other means. From the […]
- Serendipity
An accidental and fortunate discovery. A celebrated instance of serendipity in biomedical research took place in 1928 at St Mary’s Hospital in London. While studying staphylococci (staph bacteria), the physician and microbiologist Alexander Fleming happened to noticed that on a dish containing agar on which he had been growing germs, near some mold, the germs […]