Syndrome, Cushing


An abnormal growth of the pituitary gland, which can stimulate the adrenal gland;
A benign or malignant growth within the adrenal gland itself, which produces cortisol; or
Production within another part of the body (ectopic production) of a hormone that directly or indirectly stimulates the adrenal gland to make cortisol.

The neurosurgeon Harvey Cushing (1869-1939) described excessive production of cortisol by the adrenal gland due specifically to an ACTH-secreting pituitary adenoma, a benign pituitary tumor that puts out ACTH (AdrenoCorticoTropic Hormone). This drives the adrenal gland to overproduce cortisol.

Read Also:

  • Syndrome, Danlos

    50. A son with the gene is affected with the disease while a daughter with the gene is merely a carrier like her mother. Type VI EDS (the ocular-scoliotic form of EDS) is characterized by a fragile globe of the eyes, significant skin and joint laxity, and severe curvature of the spine (scoliosis). It is […]

  • Syndrome, deafness-ichthyosis-keratitis

    See Keratitis-ichthyosis-deafness syndrome.

  • Syndrome, dengue shock

    A syndrome due to the dengue virus that tends to affect children under 10, causing abdominal pain, hemorrhage (bleeding) and circulatory collapse (shock). Known also as dengue hemorrhagic fever (DHF), it starts abruptly with high continuous fever and headache plus respiratory and intestinal symptoms with sore throat, cough, nausea, vomiting, and abdominal pain. Shock occurs […]

  • Syndrome, Down

    A common chromosome disorder due to an extra chromosome number 21 (trisomy 21). Down syndrome causes mental retardation, a characteristic face, and multiple malformations. Down syndrome is a relatively common birth defect. The chromosome abnormality affects both the physical and intellectual development of the individual. Down syndrome causes mental retardation, a characteristic facial appearance, and […]

  • Syndrome, dumping

    A group of symptoms that occur when food or liquid enters the small intestine too rapidly. These symptoms include cramps, nausea, diarrhea, and dizziness.


Disclaimer: Syndrome, Cushing definition / meaning should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. All content on this website is for informational purposes only.