The anticoagulant warfarin (COUMADIN) is a known teratogen, an agent that can disturb the development of the embryo and fetus and lead to birth defects.
Warfarin taken by a woman during pregnancy can cause bleeding into the baby’s brain (cerebral hemorrhage), underdevelopment (hypoplasia) of the baby’s nose and stippling of the ends (the epiphyses) of the baby’s long bones.
Teratogen and Teratogenic drugs.
- Teratogenic drugs
thiouracil/propylthiouracil and carbimazole/methimazole. Cocaine. DES (diethylstilbestrol), a hormone. Thalidomide (Thalomid) which was approved by the FDA for the treatment of a complication of leprosy (erythema nodosum leprosum).
A type of germ cell tumor that may contain several different types of tissue and sometimes mature elements such as hair, muscle, and bone. Teratomas occur most often in the ovary, testis, and in the sacrococcygeal region (near the tailbone) in children. A teratoma may be benign or malignant.
- Teratoma, ovarian
Also called a dermoid cyst of the ovary, this is a bizarre tumor, usually benign, in the ovary that typically contains a diversity of tissues including hair, teeth, bone, thyroid, etc. A dermoid cyst develops from a totipotential germ cell (a primary oocyte) that is retained within the egg sac (ovary). Being totipotential, that cell […]
Fear of bearing a malformed child. A phobia is an unreasonable sort of fear that can cause avoidance and panic. Phobias are a relatively common type of anxiety disorder. Phobias can be treated with cognitive behavioral therapy using exposure and fear reduction techniques. In many cases, anti-anxiety or anti-depressant medication proves helpful, especially during the […]