Toll-like receptor 4
TLR4. One in a family of receptors that provide critical links between immune stimulants produced by microorganisms and the initiation of host defenses. Abbreviated TLR4.
TLR4 is a transmembrane lipopolysaccharide receptor. Activation of it causes the release of antimicrobial peptides, inflammatory cytokines and chemokines, and costimulatory molecules that initiate the innate immune response to common gram-negative bacteria. TLR4 also interacts with respiratory syncytial virus, heat-shock proteins, fibronectin, fibrinogen, and hyaluronic acid.
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Or tomo- before a consonant. A combining form meaning a cut, section, slice or layer, as might be achieved by cutting or slicing. Used in the formation of compound words such tomography. From the Greek tomos (a cutting).
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Or tom- before a vowel. A combining form meaning a cut, section, or layer, as might be achieved by cutting or slicing. Used in the formation of compound words such tomography. From the Greek tomos (a cutting).
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