Transforming growth factor
(TGF) One of several proteins secreted by transformed cells that can stimulate the growth of normal cells. Transforming growth factor alpha (TGF alpha or TGF-A) binds the epidermal growth factor receptor (EGFR) and stimulates the growth of endothelial cells (cells that line the inside of blood vessels). Transforming growth factor beta (TGF-beta or TGF-B) is found in hematopoietic (blood-forming) tissue and initiates a signaling pathway that suppresses the early development of cancer cells.
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- Transforming principle
“Assuming that the sodium desoxyribonucleate and the active principle are one and the same substance, then the transformation described represents a change that is chemically induced and specifically directed by a known chemical compound. If the results of the present study on the chemical nature of the transforming principle are confirmed, then nucleic acids must […]
- Transfusion
The transfer of blood or blood products from one person (the donor) into the bloodstream of another person (the recipient). In most situations, transfusion is done as a lifesaving maneuver to replace blood cells or blood products lost through severe bleeding. Transfusion of one’s own blood (autologous transfusion) is the safest method, but it requires […]
- Transfusion medicine
The practice of blood transfusion and blood conservation, complementary activities that ensure the best balance between safety and convenience during emergency care or surgery.
- Transgenic
Having genetic material (DNA) from another species. This term can be applied to an organism that has genes from another organism. It is understood that the foreign genes are in the transgenic animal’s germ-cell DNA and so can be transmitted from one generation to the next.
- Transient global amnesia
Attacks must be witnessed and information must be available from a capable observer. Clear-cut anterograde amnesia must be present during the attack. Clouding of consciousness and loss of personal identity must be absent and cognitive impairment must be limited to amnesia. There must be no accompanying focal neurological symptoms or signs, and epileptic features must […]